IUI

Intrauterine Insemination in Kathmandu — IUI Explained ~15–20% Per Cycle — with the Candidacy Assessment That Determines Who It Helps

IUI at Thamel Clinic — intrauterine insemination: who it suits, the ~15–20% per-cycle success, procedure and honest escalation pathway.

Medically Reviewed Content

Reviewed by: STD Specialist (MBBS, MD - Medicine)

Last medical review: June 1, 2026

Next scheduled review: December 1, 2026

This content follows evidence-based medical guidelines and is regularly updated to reflect current medical practices.

IUI — What to Know

  • IUI is less invasive: no egg retrieval or embryo culture.
  • It is appropriate for specific causes: unexplained infertility, mild male factor, cervical factors.
  • Success depends on the cause: lower than IVF but less costly.

IUI in Kathmandu

  • ~15–20% per cycle — honest success rate.
  • Candidacy first — work-up determines whether IUI fits.
  • Tubes must be open — IUI cannot bypass a blocked tube.
  • ~3–4 cycle escalation — IVF where IUI has not worked.

IUI — What It Is and Who It Helps

Intrauterine insemination — washed, concentrated sperm placed directly into uterus at moment of ovulation — is first-line fertility treatment for a defined set of candidates: unexplained infertility, mild male-factor, cervical-factor, and some anovulation.

The ~15–20% per-cycle success rate is honest — treatment helps a specific subgroup; it does not fix everything. The candidacy assessment is service — tubes open (IUI cannot bypass a blockage), sperm adequate (severe male-factor is IVF), ovarian reserve justifying approach rather than jumping to IVF, and diagnosis being one IUI addresses.

At Thamel Clinic work-up precedes treatment — semen analysis, tubal assessment (HSG), hormonal picture — before any cycle is run, because an IUI on a poor candidate is commonest fertility waste.

This page covers Intrauterine Insemination in Kathmandu in Kathmandu — confidential, non-judgmental care. Correct evaluation comes first: the actual condition or need determines which approach is appropriate, and the plan is matched to the real cause rather than generic advice. Intrauterine insemination (IUI) is a fertility treatment where washed sperm is placed directly into the uterus at ovulation. It is less invasive than IVF and appropriate for unexplained infertility, mild male factor, and cervical factors.

Who IUI Suits

The candidates: unexplained infertility ( diagnosis after a normal work-up), mild male-factor (adequate post-wash motile count — severe is IVF), cervical-factor infertility, anovulation treatable with ovulation induction, and mild endometriosis in some cases.

The poor candidates: blocked fallopian tubes (the HSG confirms patency first — IUI cannot bypass them), severe male-factor, diminished ovarian reserve where IVF is better approach, and advanced maternal age where the IUI time-cost is not justified.

Unexplained Infertility

The classic candidacy — after a normal work-up.

Mild Male-Factor

Adequate post-wash count — severe is IVF.

Tubes Must Be Open

HSG confirms patency — IUI cannot bypass a blockage.

Ovarian Reserve Adequate

AMH and hormones justify approach.

The Procedure

The cycle is monitored — ultrasound tracking of follicle development, ovulation-induction medication where used, precise timing at the LH surge or hCG trigger — and insemination is brief procedure at moment of ovulation.

The sample is washed first — motile sperm concentrated, seminal fluid removed (essential — unwashed semen in uterus causes severe cramping) — then placed via a thin catheter directly into uterus, a minutes-long procedure usually without anaesthesia.

Monitored Cycle

Ultrasound tracking — timing precise.

Sperm Washing

Concentrated and cleaned — essential for uterine placement.

Thin Catheter

The sample placed directly in uterus.

Minutes, No Anaesthesia

Brief and usually painless.

The ~15–20% Per-Cycle Rate

The honest number: ~15–20% per cycle — most couples need more than one attempt, and cumulative success builds over ~3–4 cycles before benefit of more IUI drops off. The ~15–20% is not a failure rate to despair over — it is biology of fertilization even when everything is done correctly.

The factors that push it higher or lower: age (younger patients do better), diagnosis (unexplained does better than harder indications), stimulation used, and sperm quality on day.

~15–20% Per Cycle

Honest — most couples need more than one.

Cumulative ~3–4

The success builds — then drops off.

Age Matters

Younger patients have better per-cycle rates.

Diagnosis Matters

Unexplained does better than harder causes.

The Escalation Point

The honest escalation: where ~3–4 IUI cycles have not produced a pregnancy, benefit of additional IUI drops — escalation to IVF is discussed honestly rather than repeating an approach that has not worked.

The plan from start includes this — IUI is a step in pathway, not an endpoint — so a failed cycle is a step toward next decision, not a surprise.

~3–4 Cycles

The threshold where more IUI is less useful.

IVF Escalation

The next step where IUI has not worked.

Pathway Planned

The escalation is part of plan from start.

Not Indefinite

IUI is not repeated endlessly when it has not worked.

Intrauterine Insemination in Kathmandu

What it is

Washed sperm placed directly into the uterus at ovulation.

Less invasive

Simpler than IVF — no egg retrieval or embryo culture.

Appropriate for

Unexplained infertility, mild male factor, cervical factors.

Success rates

Lower than IVF but less costly — depends on the cause.

IUI & Costs

ServiceWhat It IncludesCost (NPR)
Fertility consultationAssessment and candidacy determinationRs. 450
Work-upSemen analysis, tubal assessment, hormonesLab rate
IUI cycleMonitoring + insemination — per cyclePer cycle
Ovulation medicationWhere usedPer cycle

Transparent pricing; confirm when booking.

Why Thamel Clinic for IUI

  • Candidacy-first — work-up determines whether IUI fits.
  • Honest success rate — ~15–20% per cycle, not inflated.
  • Precisely timed — ovulation window hit correctly.
  • Escalation-aware — ~3–4 cycle threshold before IVF.
  • Confidential — private fertility consultations.

Frequently Asked Questions

What is IUI?

Intrauterine insemination — washed sperm placed in uterus at ovulation.

What is success rate?

~15–20% per cycle — cumulative over ~3–4 before escalation.

Who is IUI for?

Unexplained infertility, mild male-factor, cervical-factor, some anovulation — candidacy assessed first.

What if IUI fails?

After ~3–4 unsuccessful cycles IVF is discussed — pathway includes escalation.

Is work-up necessary?

Yes — tubes must be open and sperm adequate; an IUI on a poor candidate is waste.

Is it confidential?

Yes — private fertility consultations.

What is IUI?

Intrauterine insemination — washed sperm placed directly into the uterus at ovulation.

Who is IUI appropriate for?

Unexplained infertility, mild male factor, cervical factors — less invasive than IVF.

Still have questions? Contact us or book an appointment for personalized guidance.

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Last Updated: November 7, 2026 |Clinic: Thamel Clinic |Licensed: Registered

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