IUI

IUI Fertility Services in Nepal — Intrauterine Insemination ~15–20% Per-Cycle Success — with the Candidacy Assessment First

IUI services at Thamel Clinic — candidacy assessment, the ~15–20% per-cycle success rate, work-up and honest escalation pathway.

Medically Reviewed Content

Reviewed by: STD Specialist (MBBS, MD - Medicine)

NMC Registration:

Last medical review: June 1, 2026

This content follows evidence-based medical guidelines and is regularly updated to reflect current medical practices.

IUI in Nepal

  • ~15–20% per cycle — honest success rate; not a guarantee.
  • Candidacy first — work-up determines whether IUI fits.
  • Tubes must be open — IUI cannot bypass a blocked tube.
  • ~3–4 cycle threshold — where IUI has not worked, escalate rather than repeat indefinitely.

IUI — the First-Line Fertility Treatment

Intrauterine insemination — washed sperm placed directly into uterus at ovulation — is first-line fertility treatment for a defined set of candidates: unexplained infertility, mild male-factor, cervical-factor, and some anovulation. Its ~15–20% per-cycle success rate is honest — treatment helps a specific subgroup; it does not fix everything.

The candidacy assessment is service — fallopian tubes must be open (IUI cannot bypass a blocked tube), sperm parameters must meet a minimum threshold, ovarian reserve must justify approach rather than jumping to IVF, and diagnosis must be one IUI addresses. An IUI performed on a poor candidate is commonest fertility waste.

At Thamel Clinic work-up precedes treatment — semen analysis, tubal assessment (HSG or similar), hormonal picture (AMH, cycle-day hormones) and ovarian reserve — before any cycle is run.

Who IUI Suits

The candidates: unexplained infertility ( diagnosis after work-up is otherwise normal), mild male-factor (adequate motile sperm count after washing — severe male-factor is an IVF indication), cervical-factor infertility, anovulation treatable with ovulation induction, and mild endometriosis in some cases.

The poor candidates: blocked fallopian tubes (IUI cannot bypass them — the HSG confirms patency first), severe male-factor, diminished ovarian reserve where IVF is better approach, and advanced maternal age where the IUI time-cost is not justified.

Unexplained Infertility

The classic candidacy — diagnosis after normal work-up.

Mild Male-Factor

Adequate post-wash motile count — severe is IVF.

Tubes Must Be Open

HSG or similar confirms patency — IUI cannot bypass a blockage.

Ovarian Reserve Adequate

AMH and hormonal picture justify approach.

The Work-Up Before the Cycle

The male factor — a semen analysis establishes whether post-wash motile sperm count meets threshold for a reasonable IUI attempt; severe male-factor moves directly to IVF rather than wasting cycles. The female factor — tubal assessment (HSG or sonohysterography) confirms patency, hormonal panel (AMH, cycle-day-3 hormones) assesses ovarian reserve.

The diagnostic clarity before treatment is what makes an IUI worthwhile: an IUI on a poor candidate is not just ineffective — it costs months that a correctly-matched treatment would have used better.

Semen Analysis

Post-wash motile count — candidacy threshold.

Tubal Assessment

HSG or similar — patency confirmed before any cycle.

Hormonal Panel

AMH + cycle-day hormones — ovarian reserve.

Candidacy First

The diagnosis before treatment — honest sequence.

The Cycle — Monitoring to Insemination

An IUI cycle is monitored — ultrasound tracking of follicle development (and where used, ovulation-induction medication monitored for response) — with insemination timed at the LH surge or trigger shot.

On insemination day washed sample is prepared ( sperm concentrated and seminal fluid removed) and placed directly into uterus — a brief procedure, usually without anaesthesia, done in minutes.

Follicle Monitoring

Ultrasound tracking — cycle timed precisely.

Ovulation Induction Where Used

Monitored for response — dose adjusted.

Timed Insemination

At the LH surge or trigger — precise window.

Brief Procedure

Washed sperm placed in uterus — minutes, usually without anaesthesia.

Success Rate & the Escalation

The honest number: ~15–20% per cycle — most couples need more than one cycle, and cumulative success builds over ~3–4 cycles before benefit of more IUI drops off. Where IUI has not produced a pregnancy after ~3–4 attempts, escalation to IVF is discussed honestly rather than repeating an approach that has not worked.

The escalation conversation is part of plan from start: IUI is a step, not an endpoint — cumulative chance is explained upfront so a failed cycle is a step in pathway, not a surprise.

~15–20% Per Cycle

Honest — most couples need more than one.

Cumulative Over ~3–4

The benefit builds — then drops off.

Escalate ~3–4 Failed

IVF discussed honestly — not indefinite IUI.

The Plan Includes the Pathway

IUI is a step — escalation is part of plan.

IUI Services & Costs

ServiceWhat It IncludesCost (NPR)
Fertility consultationAssessment and candidacy determinationRs. 450
Work-upSemen analysis, tubal assessment, hormonal panelLab rate
IUI cycleMonitoring + insemination — per cyclePer cycle
Ovulation medicationWhere usedPer cycle

Transparent pricing; confirm when booking.

Why Thamel Clinic for IUI

  • Candidacy-first — work-up determines whether IUI fits.
  • Honest success rate — ~15–20% per cycle, not inflated.
  • Escalation-aware — ~3–4 cycle threshold before IVF is discussed.
  • Complete work-up — tubes, sperm, reserve — before any cycle.
  • Confidential — private fertility consultations.

Frequently Asked Questions

What is IUI?

Intrauterine insemination — washed sperm placed in uterus at ovulation.

What is success rate?

~15–20% per cycle — honest; cumulative over ~3–4 cycles before escalation.

Who is IUI for?

Unexplained infertility, mild male-factor, cervical-factor, some anovulation — candidacy assessed first.

What if IUI fails?

After ~3–4 unsuccessful cycles IVF is discussed — pathway includes escalation.

Is work-up necessary?

Yes — tubes must be open and sperm adequate; an IUI on a poor candidate is waste.

Is it confidential?

Yes — private fertility consultations.

Still have questions? Contact us or book an appointment for personalized guidance.

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Last Updated: October 19, 2026 |Clinic: Thamel Clinic |Licensed: Registered

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