Best Specialist for Genital Sores in Kathmandu Every Sore Gets a Diagnosis
A genital sore is never "just a sore" — syphilis, herpes, chancroid, trauma and fixed drug eruption all present this way, and the dangerous one (syphilis) is routinely missed. Correct diagnosis at Thamel Clinic resolves it.
Medically Reviewed Content
Reviewed by: STD Specialist (MBBS, MD - Medicine)
NMC Registration:
Last medical review: June 1, 2026
This content follows evidence-based medical guidelines and is regularly updated to reflect current medical practices.
Sore Mis-Management in Nepal
- Painless sores ignored — the syphilis chancre is trivial-seeming and routinely left.
- Topical antibiotics applied — systemic infection treated with skin cream.
- Herpes assumed — any sore given antivirals without testing.
- HIV never co-tested — ulcerative disease's HIV-risk multiplier ignored.
Sores: the Symptom That Cannot Be Guessed
"Sore" is the lay term covering the whole ulcer/lesion spectrum — and the diagnostic stakes are the same: the syphilis chancre is classically painless and indurated, easily dismissed as trivial, and the diagnosis that must never be missed; herpes is the painful grouped vesicle-ulcer; chancroid is ragged and suppurative; trauma and drug reactions mimic all three.
Every genital sore at our clinic gets the same disciplined evaluation: morphology examination, syphilis serology without exception, lesion PCR where a fresh ulcer exists, HIV co-testing (ulcerative disease multiplies HIV risk), and a biopsy pathway for anything that does not heal. The dangerous mimic is excluded before the comfortable conclusion is reached.
This page covers the sore differential, the non-negotiable tests, and treatment per cause.
The Sore Differential
Syphilis chancre
Painless, indurated, clean-based — the dangerous miss; serology confirms.
Herpes
Painful grouped vesicles → shallow ulcers; PCR confirms.
Chancroid
Ragged, painful, suppurative with tender nodes.
Trauma
Friction/injury-related; heals without treatment.
Fixed drug eruption
Same-site recurrence on drug re-exposure.
Non-healing ulcers
Persistent ulcers get biopsy — malignancy never assumed away.
The Non-Negotiable Tests
- Syphilis serology (RPR + TPHA) on every genital sore — without exception.
- Lesion PCR — herpes confirmed while the ulcer is fresh.
- HIV test — ulcerative STIs multiply HIV risk; tested together.
- Follow-up or biopsy — for anything that does not heal.
Why Sores Are Time-Sensitive
The syphilis window matters — a chancre is early syphilis, the most treatable stage, and the stage before it disseminates. Fresh-lesion PCR works best in the first days. And ulcerative disease's HIV-risk multiplier is immediate. Genital sores warrant days-level evaluation, not weeks.
Sore Evaluation & Costs
| Service | What It Includes | Cost (NPR) |
|---|---|---|
| Consultation + exam | Lesion workup. | Rs. 450 |
| Syphilis serology pair | RPR + TPHA — routine. | Rs. 1,500 – 3,000 |
| Lesion PCR | Herpes confirmation. | Rs. 5,000 – 8,000 |
| HIV test | Ag/Ab alongside. | Rs. 1,500 – 3,000 |
| Biopsy pathway | Non-healing ulcers. | Quoted on plan |
Quoted at consult.
Why Sores Are Resolved Here
- Syphilis always tested — the dangerous miss never made.
- Correct confirmation — PCR and serology matched.
- HIV co-tested — the risk multiplier addressed.
- Non-healers escalated — biopsy where a sore will not settle.
- Cause-matched treatment — not a topical guess.
Frequently Asked Questions
Is a genital sore always an STD?
No — trauma and other causes exist — but every sore gets syphilis serology because that is the one that must never be missed.
A painless sore — is it serious?
Painless and indurated is the classic syphilis chancre pattern — the presentation that most needs testing despite feeling trivial.
How fast should a sore be seen?
Promptly — fresh-lesion PCR and early syphilis detection both reward early visits.
Why is HIV tested with a sore?
Ulcerative STIs increase HIV acquisition/transmission risk — the paired test is standard.
What if the sore does not heal?
A non-healing ulcer gets biopsy consideration — persistent ulcers are escalated, not repeatedly creamed.
Still have questions? Contact us or book an appointment for personalized guidance.
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Last Updated: October 19, 2026 |Clinic: Thamel Clinic |Licensed: Registered