Modern Herpes Testing Lab in Nepal — PCR & Serology The Lesion PCR for the Acute, the Typed Serology for the Status

Herpes Testing — the Two Methods by the Question

Herpes testing is two methods matched to question: lesion PCR for a fresh sore (the ~2–12 day acute diagnostic — ~95% sensitive on fresh lesion) and typed serology for status question (the ~3–12 week window — type-specific antibodies for HSV-1 vs HSV-2).

The method is matched to presentation: a fresh sore is lesion-PCR case ( direct detection on shedding virus); a status question or an exposure-history is serology case ( antibodies detected where no lesion is present).

The honest framing: windows are biological — lesion PCR on a healing lesion is reduced sensitivity ( false-negative risk); serology too early is inconclusive — correct test at correct timing is reliable version.

This page covers Modern Herpes Testing Lab in Kathmandu — confidential, non-judgmental care. Correct evaluation comes first: the actual condition or need determines which approach is appropriate, and the plan is matched to the real cause rather than generic advice. A modern herpes testing laboratory provides lesion PCR for active outbreaks and type-specific IgG serology for past exposure — the correct method depends on whether a lesion is present.

The Lesion PCR — the Acute Diagnostic

The lesion PCR detects virus directly on a fresh sore or an early blister — ~95% sensitive within the ~2–12 day window — acute diagnostic where a lesion is present. The fresh lesion is diagnostic opportunity; a healing lesion is reduced sensitivity ( false-negative risk).

The result reports HSV-1 vs HSV-2 — type determined — type informing prognosis (the HSV-2 is genital-associated; the HSV-1 is oral-associated but genital HSV-1 is increasingly common).

The Typed Serology — the Status

The typed serology detects type-specific antibodies for HSV-1 vs HSV-2 — status question ( prior exposure, standing infection) — the ~3–12 week window for antibodies to develop.

The serology is for where no lesion is present — status question — typed result distinguishing the HSV-1 ( oral-associated, increasingly-common genital) from the HSV-2 ( genital-associated) for prognosis and counselling.

The Windows — Matched to the Question

The lesion PCR window is ~2–12 days — acute period where sore is shedding virus — method for where a fresh lesion is present. A healing lesion or a resolved one is serology question instead.

The serology window is ~3–12 weeks — antibodies take that long to develop — method for status question where no lesion is present, timed to the ~3–12 week point for reliable detection.

The Interpretation — the Chronic-Infection Context

A positive is interpreted in chronic-infection context: herpes is managed not cured — antivirals (episodic or suppressive) control it — transmission discussion (the ~50% asymptomatic shedding — transmission possible without visible lesions), and not-infidelity honesty (a positive can be a long-standing infection, not a recent acquisition).

A negative is read against timing — a too-early serology is inconclusive; a negative-lesion-PCR is acute-not-detected ( timing, healing-lesion possibility) — interpretation matching method.

Modern Herpes Testing Lab

Herpes Testing & Costs

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