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Male Sexual Dysfunction
Peyronie's Disease
Peyronie's disease is characterized by the development of fibrous scar tissue (plaque) inside the penis, resulting in curved, painful, or shortened erections.
70%
Success Rate
6-12 months for medical therapy; surgery for advanced disease
Duration
Multiple
Treatment Options
3+ Groups
May Affect
What is Peyronie's Disease?
Peyronie's disease is characterized by the development of fibrous scar tissue (plaque) inside the penis, resulting in curved, painful, or shortened erections.
Prevalence: Affects 3-10% of men; typically develops between ages 40-60
Symptoms and Signs
- •Curved or bent penis during erection
- •Pain during erection (especially early stages)
- •Palpable plaque or lump
- •Difficulty with intercourse
- •Reduced erectile function
- •Psychological distress
Causes and Risk Factors
Common Causes
- →Penile trauma (often during intercourse)
- →Genetic predisposition
- →Connective tissue disorders
- →Certain medications (beta-blockers)
- →Smoking
- →Dupuytren's contracture
Risk Factors
- ⚠️Penile trauma
- ⚠️Family history
- ⚠️Age 40-60
- ⚠️Smoking
- ⚠️Connective tissue disease
Treatment Options
Expected Outcomes: Variable outcomes; 50-60% stabilization with conservative treatment; 80-90% satisfaction with surgery
Available Treatments:
- ✓Observation and monitoring (early stages)
- ✓Oral medications (vitamin E, colchicine, pentoxifylline)
- ✓Intralesional injections (collagenase, verapamil)
- ✓Extracorporeal shock wave therapy (ESWT)
- ✓Vacuum therapy with traction
- ✓Surgical intervention (in advanced cases)
- ✓Penile implants (if ED develops)
Prevention Tips
- →Careful sexual technique
- →Treat penile injuries
- →Quit smoking
- →Communicate with partner
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